Brain cancer is the deadliest childhood cancer.

The Pediatric Neuro-oncology Consortium (PNOC) brings together the world's best 275+ clinicians and researchers to push for breakthroughs.

PNOC is a consortium with a global presence. We have collaborating centers within the United States, Europe, Asia, the Middle East and Australia.

Dedicated to finding cures for pediatric brain cancers, PNOC is translating the latest findings in brain tumor biology into better treatments for children.

These children can't wait. Pediatric brain cancer moves fast. We need to move faster.

We are a GuideStar platinum rated registered 501(c)3 give today and help accelerate research, clinical trials and cures.

Our doctors are disruptors and thoughtful innovators challenging current paradigms and rapidly advancing therapies that are globally accessible and transformative.

PNOC is developing clinical trials for the deadliest pediatric brain cancers and has dedicated working groups for Diffuse Midline Glioma/High grade Glioma/DIPG, Low grade Glioma, Medulloblastoma, Atypical Teratoid Rhabdoid Tumors (ATRT), Craniopharyngioma, Ependymoma, Germ Cell Tumors as well as Immunotherapy, Imaging, and DEI (Diversity, Equity, and Inclusion).


To lose no child to brain cancer, and to improve the quality of life for those fighting and surviving pediatric brain cancer.


To urgently raise funds, resources and awareness to support PNOC’s research and clinical trials, to ultimately improve outcomes for all children with brain tumors.


PNOC’s approach is open source and globally collaborative, making research accessible in real time, something never before seen in this field.



children in the U.S are diagnosed each year, of whom more than 500 will die.


children are estimated to be living with a brain tumor in the U.S.


years of life are lost each year to pediatric brain cancer.


despite these staggering statistics, pediatric brain cancer only receives ~1% of federal research funding.